NS 113, 510-885-4757
|Class Number||Section||Days||Room Number||Times|
|4430||2||MW||MI-2064||2 - 3:30 pm|
|4430||09SS||TTh||SC-N119||10:30 - 12pm|
Class I molecules are expressed on the surface of nearly all somatic cells and found to be associated with a small molecular weight protein called Beta-2 mictoglobulin (B2m). Together class I and B2m cooperate to promote T cell mediated destruction of virally infected and/or cancerous cells.
My current interests in the laboratory are focused on understanding the molecular basis for the role B2m plays in ensuring that effective T cell recognition and subsequent destruction occur.
- A Point Mutation in Beta-2 Microglobulin Results in Loss of Epitope Expression. Dimaano, C., Nguyen, T., Ahmed, A., Abel, E., Schultz, C. and Nieto, M. Tissue Antigens. 56: 473-475, 2000.
- Effect of B2m Mutations on the Alpha-1 Helical Region of H2-Ld. Schultz, C., Rodriguez, R., Dimaano, C., Chew, E., Li, F.M. and Nieto, M. Immunogenetics 48: 273-282, 1998.