Maria Nieto
NS 113, 510-885-4757
maria.nieto@csueastbay.edu
| Class Number | Section | Days | Room Number | Times |
|---|---|---|---|---|
| 4430 | 2 | MW | MI-2064 | 2 - 3:30 pm |
| 4430 | 09SS | TTh | SC-N119 | 10:30 - 12pm |
Class I molecules are expressed on the surface of nearly all somatic cells and found to be associated with a small molecular weight protein called Beta-2 mictoglobulin (B2m). Together class I and B2m cooperate to promote T cell mediated destruction of virally infected and/or cancerous cells.
My current interests in the laboratory are focused on understanding the molecular basis for the role B2m plays in ensuring that effective T cell recognition and subsequent destruction occur.
Recent Publications:
- A Point Mutation in Beta-2 Microglobulin Results in Loss of Epitope Expression. Dimaano, C., Nguyen, T., Ahmed, A., Abel, E., Schultz, C. and Nieto, M. Tissue Antigens. 56: 473-475, 2000.
- Effect of B2m Mutations on the Alpha-1 Helical Region of H2-Ld. Schultz, C., Rodriguez, R., Dimaano, C., Chew, E., Li, F.M. and Nieto, M. Immunogenetics 48: 273-282, 1998.
